The only grounds I removed were the branch legs from the main harness (trunk) ground to specific sensors that were being removed. Good reminder though.You may already know this but just FYI in case others are reading this and looking to do a similar swap.
Since you're reducing wire count in your loom be very cautious of ground wires. Do not eliminate or combine grounds. GM had some issues early on as they were transitioning from their Gen III to Gen IV engines and electronics where they used a common ground. With their earlier iterations it wasn't an issue but with the more sensors they were adding and relying on for data as well as multimale servos such as throttle body, purge, etc. they quickly realized that one ground wasn't enough of a current path and were experiencing limp mode symptoms. This was solved by adding multiple grounds but unfortunately one of the more common things I've seen when people try to reduce wire count is these grounds being combined. Even on some aftermarket standalone wiring harnesses for street rods/race cars I see this and it is not a good practice because if several servos are being activated it can cause just enough of a voltage drop to put the ECM into limp mode. These systems are monitoring so precisely that even a few millivolts of voltage drop or out of parameter and it will either throw a code or worse put it into limp mode. This is also why the USEPA guidelines specify that even the factory wire harness must be intact as it is an integral part of the emissions system nowadays.
Just an FYI.
Grounds are often overlooked and in my experience are the cause of the majority of automotive electrical issues.